Study Populations
The studies performed by Surrey Clinical Research Centre to date have covered many aspects of CNS research and drug development, and used a wide variety of different volunteers and patients.
Volunteers
Healthy
- Studies involved the following agents: antidepressants, anxiolytics, antihistamines, cognitive enhancers, hypnotics, neuroleptics, NSAIDs, cardiovascular agents, antidiarrhoeals, cognitive enhancers, social substances and antiepileptics
- Safety, tolerance, PK, PD
- Bioequivalence, PK, PD
- Dose ranging, PK, PD
- Shift workers
- Radar operatives
Special Populations
- Japanese subjects
Atypical Populations
- Ex-patients (anxiety, sleep disturbance)
- Caffeine-induced insomnia
- Sleep deprived subjects
- Tobacco smokers
- Benzodiazepine-impaired memory
Elderly
- Antidepressants, anxiolytics, cognitive enhancers, antidementia agents, hypnotics
- PK, PD
- Anxiety rated
- Nutritional/vitamin status rated
Patients (Including Elderly Populations) in Hospital and General Practice
- Diabetic painful peripheral neuropathy
- Major depression
- Mixed anxiety/depression
- Anxiety
- Sleep disturbance/insomnia
- Dementia (Alzheimer’s disease, vascular dementia)
- Organic psychosyndrome
- Generalised anxiety disorder (GAD)
- Surgical (anaesthesia/premedication)
- Allergy (rhinitis, hayfever)
- Accident victims
- Drug abusers