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Dr Carina Dunlop

Lecturer

Qualifications: MMath (Oxon), DPhil (Oxon)

Email:
Phone: Work: 01483 68 6524
Room no: 41 AA 04

Further information

Biography

My research focuses on the mathematical modelling of biological systems. I joined the University of Surrey as a Lecturer in Mathematics in January 2012. Prior to this I spent four years at Heidelberg University as a postdoctoral fellow, and three and a half years as a postdoctoral researcher at Oxford University. I completed my doctoral research in fluid dynamics in 2004 at the University of Oxford, where I read mathematics as an undergraduate.

Research Interests

I am interested in using mathematical and computational approaches to solve a broad range of problems in developmental biology, tissue morphogenesis and cancer modelling. A particular research focus is on the cell as a physical object, incorporating an understanding of the role of mechanical forces into models of biological processes. I draw on a diverse range of concepts in pursuing this research ranging from population modelling to the theories of fluid dynamics and elasticity theory. Currently ongoing projects include work on tissue self-organization, mechanical regulation of growth and cellular contractility.

Students:

Christoph Koke, Diplom (2010-2011, Masters level), with Prof. U.S. Schwarz. Now PhD student KIP, Heidelberg. 

Andreas Kühne, Praktikant (2010, Summer internship), with Prof. U.S. Schwarz.

Philip Murray, PhD (2004-2008),with Prof. P. K. Maini and Dr M.J. Tindall. Now postdoc at the CMB, Oxford University. 

Matt Johnston PhD (2004-2008), with Prof. P.K. Maini and Prof. S.J. Chapman.

Publications

 Earlier papers published under my maiden name Carina M. Edwards.

Journal articles

  • Murray PJ, Edwards CM, Tindall MJ, Maini PK. (2012) 'Classifying general nonlinear force laws in cell-based models via the continuum limit'. PHYSICAL REVIEW E, 85 Article number ARTN 021921
    doi: 10.1103/PhysRevE.85.021921
  • Edwards CM, Schwarz US. (2011) 'Force localization in contracting cell layers'. American Physical Society Physical Review Letters, 107 (12)
    doi: 10.1103/PhysRevLett.107.128101
    Full text is available at: http://epubs.surrey.ac.uk/315150/
  • Kanesaki T, Edwards CM, Schwarz US, Grosshans J. (2011) 'Dynamic ordering of nuclei in syncytial embryos: a quantitative analysis of the role of cytoskeletal networks'. INTEGRATIVE BIOLOGY, 3, pp. 1112-1119.
    doi: 10.1039/c1ib00059d
  • Murray PJ, Walter A, Fletcher AG, Edwards CM, Tindall MJ, Maini PK. (2011) 'Comparing a discrete and continuum model of the intestinal crypt'. PHYSICAL BIOLOGY, 8 Article number ARTN 026011
    doi: 10.1088/1478-3975/8/2/026011
  • Johnston MD, Maini PK, Chapman SJ, Edwards CM, Bodmer WF. (2010) 'On the proportion of cancer stem cells in a tumour'. JOURNAL OF THEORETICAL BIOLOGY, 266, pp. 708-711.
    doi: 10.1016/j.jtbi.2010.07.031
  • Murray PJ, Edwards CM, Tindall MJ, Maini PK. (2009) 'From a discrete to a continuum model of cell dynamics in one dimension'. PHYSICAL REVIEW E, 80 Article number ARTN 031912
    doi: 10.1103/PhysRevE.80.031912
  • Edwards CM, Howison SD, Ockendon H, Ockendon JR. (2008) 'Non-classical shallow water flows'. IMA JOURNAL OF APPLIED MATHEMATICS, 73, pp. 137-157.
    doi: 10.1093/imamat/hxm064
  • van Leeuwen IMM, Edwards CM, Ilyas M, Byrne HM. (2007) 'Towards a multiscale model of colorectal cancer'. World Journal of Gastroenterology, 13 (9), pp. 1399-1407.
  • Van Leeuwen IMM, Byrne HM, Johnston MD, Edwards CM, Chapman SJ, Bodmer WF, Maini PK. (2007) 'Modelling multiscale aspects of colorectal cancer'. AIP Conference Proceedings, 971, pp. 3-7.
  • Edwards CM, Chapman SJ. (2007) 'Biomechanical modelling of colorectal crypt budding and fission'. BULLETIN OF MATHEMATICAL BIOLOGY, 69, pp. 1927-1942.
    doi: 10.1007/s11538-007-9199-8
  • Johnston MD, Edwards CM, Bodmer WF, Maini PK, Chapman SJ. (2007) 'Examples of mathematical modeling: Tales from the crypt'. Cell Cycle, 6 (17), pp. 2106-2112.
  • Johnston MD, Edwards CM, Bodmer WF, Maini PK, Chapman SJ. (2007) 'Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer'. Proceedings of the National Academy of Sciences of the United States of America, 104 (10), pp. 4008-4013.
    doi: 10.1073/pnas.0611179104

Reports

  • Breward C, Dyson R, Edwards CM, Metcalfe P, Please CP, Zyskin M. (2004) Modelling of melt on spinning wheels. Proc. European Study Groups with Industry (ESGI) :
  • Edwards CM, Ovendon N, Rottschäfer V. (2003) Some cracking ideas on egg incubation. Proc. European Study Groups with Industry (ESGI) :
  • Breward C, Dellar PJ, Edwards CM, Kaouri K, Richardson G, Wilson S. (2002) Mathematical modelling of pipe-flow and extrusion of composite materials. Proc. European Study Groups with Industry (ESGI) :

Departmental Duties

Seminar organiser: Nonlinear Mathematics Seminar Series.