Dr Andrea Rocco

Lecturer in Mathematical Biology

Qualifications: PhD (Physics)

Email:
Phone: Work: 01483 68 6424
Room no: 30 AX 01

Further information

Biography

I graduated in Physics at the University of Pisa (Italy) in 1994, discussing a thesis in quantum field theory. In 1998 I obtained my PhD in Physics from the University of North Texas (USA), where I focused on the role of stochastic processes in classical and quantum mechanical systems.

Between 1998 and 2007 I held postdoctoral positions at the University of Barcelona (Spain), the University of Rome "La Sapienza" (Italy), CWI (The Netherlands), and the University of Oxford (UK). During this period of time, I made a gradual transition from the general fields of Statistical Mechanics and Pattern Formation towards the modelling of biological systems. In 2007 I obtained a Lectureship in Applied Mathematics at the University of Bath (UK), where I taught Mathematical Biology modules at both MSc and undergraduate levels.

In 2009 I joined the University of Surrey (UK) as Research Fellow in Systems Biology, and was appointed Lecturer in Mathematical Biology in 2012. My current focus is on developing models of bacterial metabolism and on comparing model predictions with experimental data. More in general I am interested in the modelling of deterministic and stochastic kinetics in subcellular networks. 

Research Interests

Present:

  • Models of bacterial persistence
  • Stochastic effects in subcellular networks
  • Models of melanocyte differentiation in zebrafish

Past:

  • Branching in low temperature plasmas: Analysis and simulations
  • Ageing, slow dynamics, and glassy behaviour
  • Reaction-Diffusion fronts with multiplicative noise
  • Macroscopic randomness and complex phenomena

Publications

Cellular differentiation

  • E.R. Greenhill, A. Rocco, L. Vibert, M. Nikaido, R.N. Kelsh
    An Iterative Genetic and Dynamical Modelling Approach Identifies Novel Features of the Gene Regulatory Network Underlying Melanocyte Development
    PLoS Genetics 7, e1002265 (2011)

Stochasticity in subcellular networks

  • A. Rocco
    Stochastic control of metabolic pathways
    Phys. Biol. 6, 016002 (2009)

Molecular Evolution

  • G. Lunter, A. Rocco, N. Mimouni, A. Heger, A. Caldeira, J. Hein
    Uncertainty in Homology Inferences: Assessing and Improving Genomic Sequence Alignment
    Genome Res. 18, 298 (2008)

Low temperature plasmas

  • U. Ebert, C. Montijn, T.M.P. Briels, W. Hundsdorfer, B. Meulenbroek, A. Rocco, E.M. van Veldhuizen
    The multiscale nature of streamers
    Plasma Sources Sci. Technol. 15, S118 (2006)
  • B. Meulenbroek, A. Rocco, U. Ebert
    Streamer branching rationalized by conformal mapping techniques
    Phys Rev. E 69, 067402 (2004)
  • U. Ebert, B. Meulenbroek, C. Montijn, A. Rocco, and W. Hundsdorfer
    Spontaneous branching of anode-directed streamers: conformal analysis and numerical results
    Proceedings of the XXVI International Conference on Phenomena in Ionized Gases [refereed]
    Greifswald, Germany, July 15-20, 2003
  • U. Ebert, A. Rocco, W. Hundsdorfer, and M. Arrayás
    A mechanism for streamer branching
    Proceedings of ESCAMPIG 16th - ICRP 5th (Joint European-Japanese Conference on Gas Discharges) [refereed]
    Grenoble, France, July 14-18 2002
  • A. Rocco, U. Ebert and W. Hundsdorfer
    Branching of Negative Streamers in free flight
    Phys. Rev. E 66, 035102 (2002)

Glassy dynamics

  • B. Coluzzi, A. Crisanti, E. Marinari, F. Ritort, A. Rocco,
    A New Method to Compute the Configurational Entropy in Spin Glasses
    Eur. Phys. J. B 32, 495 (2003)
  • A. Crisanti, F. Ritort, A. Rocco, and M. Sellitto
    Is the Stillinger and Weber decomposition relevant for coarsening models?
    J. Phys.: Condens. Matter 14, 1523 (2002)
  • A. Crisanti, F. Ritort, A. Rocco, and M. Sellitto
    Inherent Structures and non-equilibrium dynamics of 1D constrained kinetic models: A comparison study
    J. Chem. Phys. 113, 10615 (2000)

Pattern Formation

  • A. Rocco, L. Ramírez-Piscina, J. Casademunt
    Kinematic reduction of reaction-diffusion fronts with multiplicative noise: Derivation of stochastic sharp-interface equations
    Phys. Rev. E 65, 056116 (2002)
  • A. Torcini, A. Vulpiani, A. Rocco
    Front propagation in chaotic and noisy reaction diffusion systems: A discrete-time map approach
    Eur. Phys. J. B 25, 333 (2002)
  • A. Rocco, J. Casademunt, U. Ebert, and W. van Saarloos
    Diffusion coefficient of propagating fronts with multiplicative noise
    Phys. Rev. E 65, 012102 (2002)
  • G. Tripathy, A. Rocco, J. Casademunt, and W. van Saarloos
    Universality class of fluctuating pulled fronts
    Phys. Rev. Lett. 86, 5215 (2001)
    doi: 10.1103/PhysRevLett.86.5215
    Full text is available at: http://epubs.surrey.ac.uk/240041/
  • F.X. Magdaleno, A. Rocco, J. Casademunt
    Interface dynamics in Hele-Shaw flows with centrifugal forces: Preventing cusp singularities with rotation
    Phys. Rev. E 62, R5887 (2000)
  • A. Rocco, U. Ebert, and W. van Saarloos
    Subdiffusive fluctuations of "pulled" fronts with multiplicative noise
    Phys. Rev. E 62, R13 (2000)

Macroscopic manifestations of randomness

  • P. Grigolini, A. Rocco and B.J. West
    Fractional Calculus as a Macroscopic Manifestation of Randomness
    Phys. Rev. E 59 2603 (1999)
  • A. Rocco and B.J. West
    Fractional Calculus and the Evolution of Fractal Phenomena
    Physica A 265, 535 (1999)
  • A. Rocco and P. Grigolini
    The Markov approximation revisited: Inconsistency of the standard quantum Brownian motion model
    Phys. Lett. A 252, 115 (1999)
  • P. Allegrini, P. Grigolini, A. Rocco
    Slow motion as a thermal gradient effect
    Phys. Lett. A 233, 309 (1997)

Teaching

BMS3072 - Systems Biology: Genomes in action